The Great Immune War

An immunology adventure by Emily Lin, Seung-Hyun Brianna Ko, Taylor Senay, and Brendan Chapko, for use with Monster of the Week by Michael Sands

(Monster of the Week is copyrighted by Evil Hat Productions, LLC and Generic Games)

Adventure concept: The immune system is a complex network maintained by cells who work tirelessly to preserve the body’s health and defenses. But something’s not quite right in this body, and the immune cells can sense it. A disease is spreading and wreaking havoc, and it’s only a matter of time before the body, the only world that these immune cells know, is gone forever.

Download the Keeper’s Guide and the immune cell character sheets below:

A Misfolding Misfortune

A 5E-compatible adventure about neurodegenerative disease

Written by: Dimitris Boufidis, Freddy S. Purnell, Tammy Ray, David Sidibe, and Amanda N. Weiss

Image created using Canva.com (elements by Sketchify Japan, Aliansi Bobe, Mohamed_hassan, Frost your design, sparklestroke)

Summary of adventure: The party of adventurers have been gathered to the town of Mo’ach, where the patron fey Coimeád, whose presence sustains the land, has become ill. The player characters (PCs) will learn that the disease is neurodegenerative, meaning that it’s causing the fey’s brain cells to die. The PCs must venture into the creature’s brain and destroy the protein plaques that are causing the cells to die, so that the healer mages can restore the creature’s brain and keep their town thriving.

This adventure is designed for level 3 (3-5 characters).

Download the adventure here:

Download the accompanying science information fact sheet here: